Risperidone and the Treatment of Schizophrenia Essay

Risperidone and the Treatment of schizophrenic psychosis - Essay ExampleTherefore, this literature review proposes addressing the followingBackground Use and Mechanisms Risperidone is the most widely recommended, second-generation antipsychotic medication for schizophrenia. It blocks excess of dopamine type 2 and serotonin 5-HT2 receptors, and lack of H1 histanminergic, and alpha 2 adrenergic receptors on nerves which cause schizophrenia, by binding to the receptors (Curran & Keating, 2006 Love & Conley, 2004 Pajonk, 2004 Robson & Gray, 2007). Therefore, risperidone has effective clinical outcomes in the discourse of schizophrenia. It is more effective in bring down positive symptoms and more directly effective in change magnitude the negative symptoms than the typical antipsychotics (Parjonk, 2003). Also, in a study by Marder (cited in Parjonk, 2003), it was shown that the rate of relapse and rehospitalisation of patients receiving long risperidone therapy is much lower than those treated with typical, and other atypical antipsychotics. In addition, it has more significantly beneficial set up on the reduction of affective symptoms, cognitive symptoms, and the improvement of patients quality of life compared with typical antipsychotics. ... Therefore, patients with schizoaffective disorders can be improved rapidly by the use of risperidone. Compared with typical antipsychotics, risperidone has a lower risk of adverse effects. In the investigation by Csernansky, Mahmoud, & Brenner (cited in Parjonk, 2003), it was proved that incidents of extrapyramidal side effects (EPSs) of risperidone are more reduced than those go through with haloperidol. In particular, there is no relationship between cardiac arrest and use of risperidone therefore, it is safer and more tolerable, reducing the cardiac risk factors.Side Effects of the Use of Risperidone, Expressed in the Literature In enkindle of the numerous beneficial effects on risperidone for patients with schi zophrenia, adverse effects continue to be a broad issue relevant to its use. The most recurrent side effects are dizziness, somnolence, insomnia, agitation, and psychosis (Curran & Keating, 2006 Love & Conley, 2004). Also, weight authorise is an important side effect, which can lead to diabetes. One of the most highlighted potential adverse effects of high dose risperidone is EPSs, such as acute dystonia, akathisia, Parkinsonism and TD. In particular TD can contribute to disfunction and disturbance of a patients quality of life, such as social isolation (Courey, 2007). TD is evidenced by irregular uncontrolled movements of face, mouth, lips, trunk and limbs, such as facial tics, tongue thrusts and rocking trunk, caused by long-term antipsychotics use. Studies have shown that protract use of antipsychotic medications such as risperidone may induce TD. It was believed that the relationship between risperidone and TD is due to the insane production or excessive growth of dopamine receptors, and highly active atoms which then damage